SOME FIBROMYALGIA PATIENTS SHOW PARIPHERAL NERVE PATHOLOGIES…

fibromyalgia

According to PAIN RESEARCH, Fibromyalgia syndrome (FMS) ranks among the most enigmatic and prevalent chronic pain conditions. Researchers and clinicians have searched in vain for an underlying cause for the unexplained widespread muscle pain, fatigue, and tenderness. In recent years, FMS has come to be seen as a “central” pain disorder, arising from changes in pain processing in the central nervous system. Now several new reports show evidence for peripheral nerve abnormalities in some FMS patients that could contribute to their chronic pain.

In a separate study that appeared June 5 in Pain, Anne Louise Oaklander and her team at Massachusetts General Hospital, Boston, US, reported similar findings in a group of 27 people rigorously diagnosed with FMS: Skin biopsies from the legs revealed that 41 percent of the FMS patients had loss of small fiber innervation to levels considered clinically diagnostic for small fiber peripheral neuropathy (SFPN), a condition that can cause widespread pain.
 
A third study presented at the November 2012 meeting of the International Association for the Study of Pain by Serra showed functional abnormalities in the small nerve fibers of FMS patients to match the anatomical differences seen by Oaklander and Sommer.

Advertisements

7 thoughts on “SOME FIBROMYALGIA PATIENTS SHOW PARIPHERAL NERVE PATHOLOGIES…

  1. This is very encouraging, Bar – I’ve thought for a long time that the cause of the trouble lies in the nerves first, rather than primarily in the muscles. We’re complicated beings, we are!

    Like

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s